
Advanced Tissue Products
At A11 Biologics, we empower healthcare professionals with advanced wound care solutions backed by FDA guidelines and regulatory excellence.
We partner only with product developers and manufactures where advanced tissue products are minimally manipulated and designed to promote and improve patient outcomes and results.

Sentry
Dehydrated Two-Layer Amnion Matrix
Activate
Dehydrated Full Thickness Placental Allograft composed of Amnion, Intermediate and Chorion
Palisade
Dehydrated Amnion/Chorion/Amnion Allograft
XCELL Amnio Matrix
Full Thickness Lyophilized Amniotic Allograft
Amnio-Maxx
Dehydrated Dual-Layer Amniotic Allograft

Amnio-Maxx® Dual Layer Amnion Allograft
Biologic surgical barrier composed of two layers of amniotic membrane, offering double the concentration of natural growth factors to support the body’s regenerative response. Designed for use in a range of surgical applications—including laparoscopic and robotic procedures—its thicker structure allows for easy handling and placement without orientation restrictions. The graft is chorion-free and immune privileged, helping reduce the risk of adverse immune response. Engineered for tensile strength and controlled resorption, it offers mechanical stability while delivering anti-inflammatory, anti-microbial, and anti-scarring properties. Amnio-Maxx is recovered from donated placental tissue after live births in the U.S., processed through a proprietary cleansing and sterilization method to ensure safety and performance.
Billing Code:
HCPCS Level II: Q4239 – Amnio-Maxx, per square centimeter, ASP April 2025: $2349.924
Available Sizes and Product Codes:
2cm x 2cm, AMN-22
2cm x 3cm, AMN-23
2cm x 4cm, AMN-24
4cm x 4cm, AMN-44
4cm x 6cm, AMN-46
4cm x 8cm, AMN-48

Xcell Amnio Matrix® next-generation, lyophilized amniotic membrane
Designed for ease of use in advanced wound care and surgical applications. Engineered with LYOTEK® technology, it preserves the native extracellular matrix and growth factor content, delivering a biologically active barrier that promotes reepithelialization. Thicker and more opaque than traditional grafts, Xcell Amnio Matrix is flexible, dry, and requires no rehydration—allowing simple application and reliable performance in both chronic and surgical wounds. Its outer basement membrane serves as a natural physiological barrier, while ambient temperature storage ensures convenience for clinicians without sacrificing efficacy.
Clinical Applications:
Diabetic Foot Ulcers
Venous Leg Ulcers
Pressure Wounds
Surgical and Reconstructive Wounds
Billing Code:
HCPCS Level II: Q4280 – Xcell Amnio Matrix, per square centimeter, ASP April 2025: $3246.048
Available Sizes and Product Codes:
2cm x 2cm, XAM-0202
2cm x 4cm, XAM-0204
4cm x 4cm, XAM-0404
4cm x 7cm, XAM-0407

Activate™ Placental-Derived Allograft is a multi-layered AIC graft
Advanced wound covering composed of amnion, chorion, and the intermediate (spongy) layer of the placenta. Designed as a biological barrier and wound matrix, Activate™ leverages the full structural and biochemical profile of placental tissue to support tissue repair across a broad range of acute and chronic wound environments. Its dual-membrane architecture provides a balance of strength and flexibility, while the preserved extracellular matrix delivers key components such as collagen types I, III, IV, and V, laminin, fibronectin, proteoglycans, and hyaluronic acid—supporting a regenerative environment.
Recovered from full-term cesarean deliveries with donor consent, all tissues are rigorously screened per FDA and AATB standards and sterilized to a sterility assurance level (SAL) of 10⁻⁶. Activate™ offers clinicians a versatile, ready-to-use allograft that maintains the native integrity of placental tissue while ensuring safety, consistency, and ease of use.
Clinical Use Cases:
Chronic wounds (e.g., diabetic ulcers, venous leg ulcers)
Acute wounds
Surgical and post-operative wound coverage
Reconstructive procedures
Billing Code:
HCPCS Level II: Q4301 – Activate™ Matrix, per square centimeter, ASP April 2025: $1896.761
Available Sizes and Product Codes:
2cm x 2cm, ACT-27222
2cm x 4cm, ACT-27224
4cm x 4cm, ACT-27244
4cm x 8cm, ACT-27248

Palisade™ Placental-Derived Allograft is a dual-membrane
Dehydrated tissue graft composed of both the amnion and chorion layers of the placenta. Designed to serve as a biologic wound covering or skin substitute, Palisade™ supports healing across a wide range of acute and chronic wounds, particularly moderate-to-deep wound beds. The graft retains the structural integrity of the native extracellular matrix, including critical proteins such as collagen (Types I, III, IV, V), laminin, fibronectin, proteoglycans, and hyaluronic acid—making it an effective barrier and scaffold for tissue repair.
Harvested from full-term cesarean deliveries with full donor consent, all Palisade™ tissues undergo extensive screening and terminal sterilization (SAL 10⁻⁶) to meet FDA and AATB standards. Its unique dual-layer format and minimal manipulation ensure both safety and biological performance in surgical, inpatient, or outpatient wound care settings.
Clinical Use Cases:
Chronic wounds
Acute surgical wounds
Skin substitutes for complex wound beds
Reconstructive wound healing
Billing Code:
HCPCS Level II: Q4350 – Palisade™ Matrix, per square centimeter, ASP Pricing: $3500.00
Available Sizes and Product Codes:
2cm x 2cm, PAL-26222
2cm x 4cm, PAL-26224
4cm x 4cm, PAL-26244
4cm x 8cm, PAL-26248

Sentry™ Placental-Derived Allograft is a single-layer membrane
Dehydrated allograft developed as a biologic wound covering and protective barrier for acute and chronic wound applications. Minimally manipulated and dehydrated, Sentry™ retains the structural and biochemical properties of native amnion, offering a thin yet compact extracellular matrix that conforms closely to wound surfaces. Its rich composition of collagen (Types I, III, IV, and V), laminin, fibronectin, proteoglycans, and hyaluronic acid supports tissue repair, reduces inflammation, and promotes a moist wound environment.
Recovered from full-term cesarean deliveries with donor consent, all tissues are rigorously screened per FDA and AATB guidelines and sterilized to a SAL of 10⁻⁶. Sentry™ is ideal for shallow-to-moderate wound beds and provides clinicians with a reliable and easy-to-use biologic dressing for in-office, outpatient, or inpatient care settings.
Clinical Use Cases:
Diabetic foot ulcers
Venous leg ulcers
Surgical incisions
Partial-thickness wounds
Skin substitutes for shallow or moderate wounds
Billing Code:
HCPCS Level II: Q4348 – Sentry™ Matrix, per square centimeter, ASP Pricing: $1950.00
Available Sizes and Product Codes:
2cm x 2cm, SEN-26222
2cm x 4cm, SEN-26224
4cm x 4cm, SEN-26244
4cm x 8cm, SEN-26248